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PhD student position in the Cell Division and Cytoskeleton group at the Danish Cancer Institute (DCI)



Strandboulevarden 49, 2100 København Ø, Danmark

ID: 2410087
Indrykket for 123 dage siden

The Cell Division and Cytoskeleton group, headed by Dr. Marin Barisic, is looking for a highly motivated and enthusiastic PhD student to join the Danish Cancer Institute (DCI).

About us
DCI is a cancer research institute within the Danish Cancer Society, whose research is heavily focused on basic biology and epidemiology, complemented with translational ambitions. DCI is uniquely positioned as a high-profile research center with strengths that build on excellent research, collaboration, curiosity and communication. The research at DCI is organized in 19 research groups and 5 core facilities. The institute has an international and multidisciplinary research environment with more than 250 researchers, students and technical personnel coming from more than 20 different countries.

Basic science is at the heart of the process that discovers new diagnostic and therapeutic possibilities. The Cell Division and Cytoskeleton group comprises a young, international, collaborative team that investigates molecular mechanisms underlying chromosomal and cytoskeletal dynamics, whose alterations during the cell cycle promote aneuploidy and metastasis, and consequently facilitate tumorigenesis. Our main aim is to use the knowledge we generate for setting up new therapeutic strategies. We investigate:

  • mechanisms of chromosome congression and segregation during mitosis
  • regulation of microtubule dynamics during cell division and cell migration
  • the impact of tubulin post-translational modifications on the activity of cytoskeletal motor proteins and their roles in chromosomal and cellular movements

For more information please visit our website.

About the position
The successful candidate will join an exciting project focused on the roles of post-translational modifications of tubulin (the so-called tubulin code) in microtubule dynamics, cell division and cell migration, and their impact on health conditions, such as cancer. To understand how tubulin code affects cancer-related processes, the project will investigate the impact of tubulin modifications on the activity and function of molecular motors and microtubule-associated proteins. This will include application of cutting-edge molecular cell biology and biochemistry methods, such as gene editing-based generation of stable cell lines for labeling and rapid targeted degradation of endogenous proteins, advanced live-cell imaging (including super-resolution microscopy), protein production and purification, and drug-screening.

About you
We are looking for a highly driven, motivated and enthusiastic candidate with the following qualifications:

  • A master’s degree in molecular biology, biochemistry, cell biology or similar
  • Experience at the bench with basic laboratory methods in molecular/cell biology and biochemistry
  • Experience with confocal and other types of microscopy is an advantage
  • Excellent oral and written communication skills in English
  • High level of motivation, commitment and creativity
  • The ability to work in a collaborative, international environment, both independently and as part of a team

We offer
We offer creative and stimulating working conditions in a dynamic and high-profile international research environment. The laboratories are equipped with modern interior and state-of-the-art technology, located in a pleasant and beautiful area near central Copenhagen. Our research facilities include several core facilities, including a high-end microscopy and animal facility, as well as histology and bioinformatics. You will join a dynamic working atmosphere with weekly seminars, invited speakers, a young researcher association, as well as strong administrative and technical support. We offer several benefits for the personnel, such as an excellent canteen, a daily selection of free fruit, and a sports and art association. The everyday working language in the laboratory is English.

As a PhD student, you will be enrolled at the University of Copenhagen, Faculty of Health and Medical Sciences.

We offer a fully-funded 3-year PhD contract. The position is full-time (37 hours a week with lunchbreak included), and salary will be provided according to the current agreements between the Danish Cancer Society and the Danish Conferation of Professional Associations (Akademikerne).

Additional information
More information can be obtained directly from group leader Marin Barisic, e-mail: [email protected]

Application and closing date for applications
The deadline for application is December 22, 2023. The selected candidates will be invited for an interview in the beginning of January 2024. The position is available from February 1, 2024.

The application should be written in English and must be submitted electronically via the link 'Apply for the position' ('Søg stillingen') below.

The application should contain:

  • A motivated letter of application (max. 1 page)
  • A short curriculum vitae
  • A copy of the MSc diploma
  • 1-2 references/letters of recommendation from previous working place

One of three Danes contract cancer at some point in their lives. Two of three have a family member suffering from cancer. Faced with these numbers, the Danish Cancer Society aims to unite the Danish population in a strong, active community against cancer, and you can help make an important difference! 

As an association, the Danish Cancer Society recognizes the value of not all of us being the same – diversity makes us smarter and better. Therefore, we encourage everyone who can see themselves in this position to apply for it. We are interested in you and your personal and professional skills, and we look forward to hearing from you. We promise you good colleagues who will welcome you and help you navigate through your new everyday life in our wide-ranging organization and association. We are committed to ensuring that you have an exciting and good working life with us at the Danish Cancer Society with an important purpose as well as professionalism, community and flexibility in various ways. And, of course, the working hours are smoke-free!

If you want to know more about working with us at the Danish Cancer Society, we encourage you to go to www.cancer.dk/om-os/job-og-karriere (right click to translate into English).

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