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Forsker søges til Psykiatrisk Afdeling Odense - Universitetsfunktion i 2 år

Research fellow (post-doc) in stem-cell based translational Psychiatry

The Department of Psychiatry, Odense is looking for highly motivated, talented, and experienced research fellow for the Patients centered Laboratory of Translational Psychiatry.  Researchers interested in cell based cutting-edge techniques for modeling and studying psychiatric disorders are strongly encouraged to apply.

Are you interested to join an interdisciplinary team working in an innovative stem cell laboratory? Would you like to be a part of a creative team developing pioneering stem-cell based techniques for modeling and studying mental health and psychiatric disorders? Would you like to make a difference for patients? Then we offer meaningful work in an exciting working environment. The stem cell laboratory for translational Psychiatry at the Research Unit at the Department of Psychiatry, Odense are looking for an experienced, committed and motivated laboratory technician for applying cutting edge stem cell technology, organizing the daily work in the lab, developing and establishing new and advanced methods contributing to solving the riddle of the neurobiology of psychiatric diseases.

About the research

Our overall aim is to understand the key molecular mechanisms of psychiatric disorders like neurodevelopmental disorders (autism, schizophrenia) and affective disorders.

We generate patients’ derived induced pluripotent stem cells (iPSC) and differentiate them into different cell types (e.g. astrocytes and neurons) as well as in three dimensional brain organoids, recapitulating critical points in neurodevelopment. The downstream analysis of brain organoids aims to investigate how phenotype, transcriptome and proteome are remodel in psychiatric disease like e.g. autism and how they correlate with cellular metabolism.

About the position

The Tasks include:

  • Generating and characterizing induced pluripotent stem cells (iPSC)
  • Differentiating iPSC into various cell types e.g. neurons and glial cells
  • Deriving and maintaining brain organoids (mini-brains) in ex vivo cultures
  • Developing and optimizing research protocols for stem cell research in psychiatry
  • Sustaining the biobank – fibroblasts, iPSC, astrocytes, neurons
  • Performing standard molecular biology techniques ELISA, Western blot, qPCR
  • Multi-omics Analysis (in collaboration)
  • Performing cryosectioning and immunocytochemistry
  • Weekend shifts

Qualifications for the position

  • You hold a MSc or a PhD in Life science and have solid laboratory experience
  • You have a strong background in stem cell technology, cellular and molecular biology
  • Strong experience in generating and maintaining iPSC is mandatory (working experience 1-2 years within the field)
  • Experience with DNA, RNA and protein analysis (e.g. methods like qPCR, ELISA, Western blot etc.
  • Experience with fluorescent microscopy)
  • You are strong in verbal and written communication both in Danish and English
  • Confident with IT, including the Office package, GraphPad
  • Eager to learn, develop and adapt new methods and protocols
  • Organizing and supporting the daily work in the lab (ordering of e.g. basic laboratory items, chemicals, cell culture media, maintenance of equipment etc.)
  • You have the ability to independently envision, plan and execute a research project.
  • You have excellent English skills (written and spoken).
  • Skills within data analysis and reporting of data
  • Confident with IT, including the Office package, GraphPad
  • Flexible and can keep focus in pressured situations without losing your good mood
  • You have an analytical sense and problem-solving ability

Personal characteristics

  • You are loyal and committed
  • You are creative and a problem-solver
  • You have good collaborative skills and are helpful
  • You like to work independently
  • You find it motivating being part of and developing a small team
  • You are good planner
  • You have a flexible attitude
  • Enjoy some routine work

What do we offer:

We offer an exciting employment in an international atmosphere focusing on innovative research for the benefit of the patients and surrounding community. We emphasize a high degree of professionalism among our employees, and competence development is an organizational nature. We are a family friendly employer and offer flexibility in your career path.

 

Start: Preferably March 2020 or after agreement

Duration: 2 years

Working hours per week: 37

Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization- (after qualification between 375 000-600 000 DK/50.000-81.000 Euros.)

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

We offer an exciting and challenging job in an international atmosphere focusing on research, education, innovation and government services for the benefit of the patients and surrounding community. We emphasize a high degree of professionalism among our employees, and competence development is an organizational nature. We have great flexibility in the job.

Application and contact

We should receive your online application no later than 29th of February, 2020. The application must include the following documents/attachments:

1. Motivation letter of application (max. one page) detailing the basis on which the applicant scientific qualifications meet the requirements for this position.

2. CV incl. education, work/research experience, language skills and other skills relevant for the position.

3. A certified/signed copy of MSc/PhD certificate.

4. List of publications.

The application must be written in English. The interviews will be held on ongoing basis until the filling the position.

For further information regarding the position, please contact Mirolyuba Ilieva, milieva@health.sdu.dk.

 

 


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