Gem job

PhD fellowship: the AIM (ABL-class Imatinib pharmacokinetics/-dynamics Monitoring) study



A position for a 3-year full-time position as PhD student (research assistant; expected start: Fall 2021) is available at Rigshospitalet for a highly motivated and independent MD with interest in hematology/oncology and pharmacology.

The job: We offer an exciting job in an international environment with the possibility of working at the interface of pre-clinical/laboratory-based activities and clinical activities at pediatric/adult clinical departments of hemato-oncology.

This project focuses on personalized medicine in the setting of tyrosine kinase inhibitor therapy, a flagship for molecularly targeted therapy in cancer used for a large and still expanding group of hematological cancers in both children and adults, the BCR-ABL1-positive/-like leukemias. How can we tailor the treatment to reduce toxicities (increase quality of life) and improve efficacy (cure rate) for each patient?

You will be involved in

- systematic review methodology and meta-analysis within the Cochrane collaboration exploring the utility of therapeutic drug monitoring of tyrosine kinase inhibitors

- laboratory-based activities including mapping of pharmacokinetics/-dynamics of tyrosine kinase inhibitors in a clinical practice setting in close collaboration with the clinical departments (aim: improve improve efficacy/cure rates and reduce toxicity/increase quality of life)

- targeted cytogenetic profiling exploring underlying mechanisms for treatment resistance/failure

Duration:: We offer a full-time position (start can be negotiated) including preparation (1 month) for a 3-year contract position as a PhD student (est. start in Fall 2021).

For additional information please contact Cecilie Utke Rank, MD, PhD, Tel: +45 2685 8297 / E-mail: cecilie.utke.rank@regionh.dk

Work place: The multi-institutional research is coordinated by the Department of Pediatrics and Adolescent Medicine, Rigshospitalet; the Department of Hematology, Rigshospitalet; and the Department of Clinical Pharmacology, Bispebjerg and Frederiksberg University Hospital.

The PhD student’s workplace will be at the Pediatric Oncology Research Laboratory (Bonkolab), Rigshospitalet. Bonkolab bridges preclinical and clinical work housing staff for (1) biochemical analyses (2 senior researchers; 1 coordinating laboratory technician, 8 full-time lab technicians, 8 clinical trial nurses); (2) biostatistics; (3) bioinformatics as well as (4) more than20 PhD students and 8 postdocs (in total 120 employees). Bonkolab is the only site in Denmark that has established and runs pharmacokinetic analysis of tyrosine kinase inhibitors and the laboratory is coordinating the Danish Cancer Society Research Centre CONTROL (Childhood Oncology Network Targeting Research, Organization & Life expectancy).

PhD supervisors:

- Kjeld Schmiegelow, MD, DMSc, professor; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

- Christen Lykkegaard Andersen, MD, PhD, DMSc, professor; Department of Hematology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

- Cecilie Utke Rank, MD, PhD; Department of Hematology, Rigshospitalet, University of Copenhagen,

- Kim Peder Dalhoff, MD, DMSc, professor; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark

Collaborators of the project:

Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital. Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital. Proteomics Program CPR, Olsen Group, Faculty of Health and Medical Sciences, University of Copenhagen. Biotech Research & Innovation Centre (BRIC), University of Copenhagen.

Department of Pediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen University Hospital. Department of Pediatric Hematology and Oncology, Odense University Hospital. Children and Adolescent Health, Aarhus University Hospital. Department of Pediatric Cancer and Blood Disorders, Oslo University Hospital.

Department of Hematology, Rigshospitalet, Copenhagen University Hospital. Department of Hematology, Zealand University Hospital, Roskilde. Department of Hematology, Odense University Hospital. Department of Hematology, Aarhus University Hospital. Department of Hematology, Oslo University Hospital.

Requirements & qualifications:

- MD with successfully completed KBU

- Work experience in clinical hematology/oncology

- Excellent written and spoken English communication skills

- Some research experience and publications in peer-reviewed journals

- High level of motivation and able to work independently

- Structured approach to documentation and data management

Salary and terms of employment: Salary and terms of employment follow current Danish agreements and regulation for similar positions.

Application: The application should include the following items:

• A cover letter (max 1 page) describing your background, personal qualities, research interests and specific reasons for applying for this position.

• Curriculum vitae (max 3 pages).

• List of peer reviewed publications. You may include manuscripts that have been accepted for publication or are in review.

• Transcripts of Diplomas (Master’s degree or equivalent).

• References: Please include contact details for two persons willing to provide you with a reference. Briefly state your personal relationship with them. Reference persons will only be contacted, if you are among the final candidates being considered for the position.

The chosen candidate will be requested to formally apply for enrolment as a PhD student at the PhD school of Health and Medical Sciences, University of Copenhagen.

The application should be written in English and submitted electronically.

Deadline: May 7, 2021 (23:59 CET) A few selected candidates will be invited for a personal interview in Week 19 at Rigshospitalet. The personal interview will be conducted in Danish.


Gem job
ellerDownload

Du har ikke vedlagt dokumenter til din ansøgning. Klik på 'OK' knappen nedenfor for at sende din ansøgning alligevel, eller klik på knappen "Annuller" og vedhæft dokumenter, før du sender din ansøgning igen.

Modtag jobannoncer der minder om dette job i din indbakke.Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.

Andre job der matcher din søgning

PhD fellow in Exolife Science, project 2 in the synergy project: "Effects of bacteria on atmospheres of Earth, Mars, and exoplanets" at the Department of Chemistry

KU - SCIENCE - NBI

København Ø
The Department of Chemistry, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Exolife Science, understood as the overlap field between chemistry, astronomy, physics and biology, commencing the 15th of August 2021 or as...
Indrykket:5. marts 2021

PhD fellow in Exolife Science, project 1 in the synergy project: "Effects of bacteria on atmospheres of Earth, Mars, and exoplanets", at the Department of Biology

KU - SCIENCE - NBI

København Ø
The Department of Biology, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Exolife science, understood as the overlap field between biology, physics, chemistry and astronomy, commencing the 15th of August 2021 or as s...
Indrykket:5. marts 2021

PhD fellow in Human-Computer Interaction and Social Robotics

KU - SCIENCE - DATALOGISK INSTITUT - UP1

København Ø
Department of Computer Science Faculty of Science University of Copenhagen Department of Computer Science, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Human-Computer Interaction, Haptics, and or Social Robotics co...
Indrykket:4. marts 2021

PhD fellow in Neuroendocrinology and Physiology

KU - SCIENCE - BIO SNM

København Ø
Department of Biology, Faculty of Science at the University of Copenhagen is offering a PhD scholarship in Neuroendocrinology and Physiology commencing 1 July 2021 or as soon as possible thereafter. Description of the scientific environment The Halb...
Indrykket:5. marts 2021

PhD position in the EU funded project H2020-MSCA-ITN SAPIENS "Sustainability And Procurement in International, European, and National Systems"

KU - JUR - Fakultetet, Co Søndre Campus

København S
ORGANISATION COMPANY Faculty of Law University of Copenhagen RESEARCH FIELD Law RESEARCHER PROFILE Early Stage Researcher (ESR) APPLICATION DEADLINE 15th April 2021 LOCATION Copenhagen Denmark TYPE OF CONTRACT Temporary (36-months fixed duration) JO...
Indrykket:8. marts 2021

Mere af samme slags?

Modtag jobannoncer der minder om dette job i din indbakke.




Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.

Andre job der matcher din søgning

PhD fellow in Exolife Science, project 2 in the synergy project: "Effects of bacteria on atmospheres of Earth, Mars, and exoplanets" at the Department of Chemistry

KU - SCIENCE - NBI

København Ø
The Department of Chemistry, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Exolife Science, understood as the overlap field between chemistry, astronomy, physics and biology, commencing the 15th of August 2021 or as...
Indrykket:5. marts 2021

PhD fellow in Exolife Science, project 1 in the synergy project: "Effects of bacteria on atmospheres of Earth, Mars, and exoplanets", at the Department of Biology

KU - SCIENCE - NBI

København Ø
The Department of Biology, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Exolife science, understood as the overlap field between biology, physics, chemistry and astronomy, commencing the 15th of August 2021 or as s...
Indrykket:5. marts 2021

PhD fellow in Human-Computer Interaction and Social Robotics

KU - SCIENCE - DATALOGISK INSTITUT - UP1

København Ø
Department of Computer Science Faculty of Science University of Copenhagen Department of Computer Science, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Human-Computer Interaction, Haptics, and or Social Robotics co...
Indrykket:4. marts 2021

PhD fellow in Neuroendocrinology and Physiology

KU - SCIENCE - BIO SNM

København Ø
Department of Biology, Faculty of Science at the University of Copenhagen is offering a PhD scholarship in Neuroendocrinology and Physiology commencing 1 July 2021 or as soon as possible thereafter. Description of the scientific environment The Halb...
Indrykket:5. marts 2021

PhD position in the EU funded project H2020-MSCA-ITN SAPIENS "Sustainability And Procurement in International, European, and National Systems"

KU - JUR - Fakultetet, Co Søndre Campus

København S
ORGANISATION COMPANY Faculty of Law University of Copenhagen RESEARCH FIELD Law RESEARCHER PROFILE Early Stage Researcher (ESR) APPLICATION DEADLINE 15th April 2021 LOCATION Copenhagen Denmark TYPE OF CONTRACT Temporary (36-months fixed duration) JO...
Indrykket:8. marts 2021