PhD student position in cranial pain mechanisms


Department of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet, Denmark

We are looking for outstanding and highly motivated candidates with background in neurobiology, pharmacology and scientific methodology.
We employ a wide range of different biochemical methods and animal models to address our scientific questions. The primary responsibility includes conducting research with a clear translational focus. The development of different methods to achieve results of high quality and of different character is desirable.

Project title: Detection and function of neuropeptides in the trigeminal ganglion and mechanisms involved in controlling messenger molecule release.

Background: This PhD is designed to develop the understanding of cranial pain mechanisms such as those associated or involving clinical conditions such as migraine and trigeminal neuralgia. The work will center around the trigeminal system – the trigeminal neurons and glial cells, its central and peripheral ramifications, and the neuronal messenger molecules associated cells.

Main aim and Importance: To develop methods to evaluate neuropeptides and their receptors function in different parts of the trigeminovascular system. The work will have importance in understanding cranial pain conditions.

Qualifications: The PhD work will involve several basic laboratory methods: It will be of considerable value that the candidate show evidence of knowledge in immunohistochemistry (a key method) as well as of organ culture and myography of vascular smooth muscle. It is important that the candidate shows genuine interest and willingness to learn, both the theoretical side as well as the practical part of our laboratory environment. Good collaborative ability is appreciated.
The candidate should be familiar with basic experiments and having approved certificate to handle laboratory animals is an advantage. It would be an additional advantage if the candidate has experience with handling rodents and dissecting tissues.

The position is a 3 year position. The starting date will be after agreement.

Application: The CV including a publication list, copy of latest degree certificate, a description of previous research and other activities of relevance for the position, including documents showing expierence in animal experiments and a brief description of current research interest should be submitted (total maximum of one page). Names and addresses of at least two people able to provide references for the candidate should also be provided.

Information: Professor Karin Warfvinge (Karin.Birgitta.Warfvinge@regionh.dk)


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