Gem job

Postdoctoral Fellowship in Single Cell and Synthetic Biology

The Schmidt group at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, invites applications from outstanding candidates who are interested in joining our group as a postdoctoral fellow. The position is available from 1 August 2022, or as soon as possible thereafter.

Research project
Research in the Schmidt group focuses on  transcriptional coordination of macrophage diversity and plasticity in metabolic health and disease. For this, we combine single cell analyses of clinical samples and viral targeting strategies in animal models. In a project recently funded by the Lundbeck Foundation, we will develop a new method for generation of cell type specific viral drivers.

The recent explosion in single cell sequencing technologies has unravelled a remarkable heterogeneity and plasticity of cell types within and across organs throughout the body, however, tools to specifically target specific cell types and states to explore their importance for development, physiology, and homeostasis are lacking. In this project, you will help bridge this gap by developing and testing different computational and experimental strategies for learning the cis regulatory code of specific cell types in vivo. This knowledge will be transformed into a method for rapid development of synthetic viral drivers and single cell assessment of their cell type specificity.

We expect the project to outline a general strategy for rapid development of tools to study rare cell types in their in vivo context. This may involve loss of function studies by delivery of RNAi or CRISPR systems for single gene studies or for pooled single cell screens or lineage tracing by delivery of fluorescence markers. The project thereby also has the potential to improve specificity of gene therapies in the future.

Postdoc qualifications/requirements
We are looking for a highly motivated, dedicated, and ambitious candidate with:

  • A PhD degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Biology.
  • Experience with cell biology or NGS data analysis. Experience with cloning, virus production, animal work, and/or transcriptional regulation is considered an advantage.
  • Documented experience leading a research project.
  • Strong communication and collaborative skills and a desire to work in an interdisciplinary environment.
  • Proficiency in spoken and written English.

 

Deadline: 1 June 2022.

Please see the full call, including how to apply, on www.sdu.dk.

Skriv i din ansøgning, at du fandt jobbet på ofir.dk


ellerGem job

Du har ikke vedlagt dokumenter til din ansøgning. Klik på 'OK' knappen nedenfor for at sende din ansøgning alligevel, eller klik på knappen "Annuller" og vedhæft dokumenter, før du sender din ansøgning igen.

Modtag jobannoncer der minder om dette job i din indbakke.Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.

Andre job der minder om dette

Postdoc position on planning and control of roboti...

Syddansk Universitet

Odense M
SDU Robotics, part of the Maersk Mc-Kinney Moller Institute, University of Southern Denmark (SDU), invites applications for a fully funded Postdoc position in the area of model- and simulation-based planning and control of robotic production operatio...
27. april 2022

Postdoc on Formal Demography of Fertility Patterns

Syddansk Universitet

Odense M
For the ERC Consolidator Grant "Towards a transdisciplinary demographic theory of birth and death trajectories", awarded to Annette Baudisch, the Danish Centre for Population Research at the Interdisciplinary Centre on Population Dynamics (CPop), Uni...
28. april 2022

Postdoc Position in Microbe-mineral Interactions

Syddansk Universitet

Odense M
We are looking for a postdoctoral scientist to join the lab of Amelia Rotaru at Nordcee, a section at the Department of Biology at the Faculty of Science, University of Southern Denmark. The lab conducts research in ecophysiology with a particular fo...
10. maj 2022

Postdoctoral Fellowship in Single Cell and Synthetic Biology

The Schmidt group at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, invites applications from outstanding candidates who are interested in joining our group as a postdoctoral fellow. The position is available from 1 August 2022, or as soon as possible thereafter.

Research project
Research in the Schmidt group focuses on  transcriptional coordination of macrophage diversity and plasticity in metabolic health and disease. For this, we combine single cell analyses of clinical samples and viral targeting strategies in animal models. In a project recently funded by the Lundbeck Foundation, we will develop a new method for generation of cell type specific viral drivers.

The recent explosion in single cell sequencing technologies has unravelled a remarkable heterogeneity and plasticity of cell types within and across organs throughout the body, however, tools to specifically target specific cell types and states to explore their importance for development, physiology, and homeostasis are lacking. In this project, you will help bridge this gap by developing and testing different computational and experimental strategies for learning the cis regulatory code of specific cell types in vivo. This knowledge will be transformed into a method for rapid development of synthetic viral drivers and single cell assessment of their cell type specificity.

We expect the project to outline a general strategy for rapid development of tools to study rare cell types in their in vivo context. This may involve loss of function studies by delivery of RNAi or CRISPR systems for single gene studies or for pooled single cell screens or lineage tracing by delivery of fluorescence markers. The project thereby also has the potential to improve specificity of gene therapies in the future.

Postdoc qualifications/requirements
We are looking for a highly motivated, dedicated, and ambitious candidate with:

  • A PhD degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Biology.
  • Experience with cell biology or NGS data analysis. Experience with cloning, virus production, animal work, and/or transcriptional regulation is considered an advantage.
  • Documented experience leading a research project.
  • Strong communication and collaborative skills and a desire to work in an interdisciplinary environment.
  • Proficiency in spoken and written English.

 

Deadline: 1 June 2022.

Please see the full call, including how to apply, on www.sdu.dk.

Skriv i din ansøgning, at du fandt jobbet på ofir.dk


+
Gem

Mere af samme slags?

Modtag jobannoncer der minder om dette job i din indbakke.




Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.

Andre job der minder om dette

Postdoc position on planning and control of roboti...

Syddansk Universitet

Odense M
SDU Robotics, part of the Maersk Mc-Kinney Moller Institute, University of Southern Denmark (SDU), invites applications for a fully funded Postdoc position in the area of model- and simulation-based planning and control of robotic production operatio...
27. april 2022

Postdoc on Formal Demography of Fertility Patterns

Syddansk Universitet

Odense M
For the ERC Consolidator Grant "Towards a transdisciplinary demographic theory of birth and death trajectories", awarded to Annette Baudisch, the Danish Centre for Population Research at the Interdisciplinary Centre on Population Dynamics (CPop), Uni...
28. april 2022

Postdoc Position in Microbe-mineral Interactions

Syddansk Universitet

Odense M
We are looking for a postdoctoral scientist to join the lab of Amelia Rotaru at Nordcee, a section at the Department of Biology at the Faculty of Science, University of Southern Denmark. The lab conducts research in ecophysiology with a particular fo...
10. maj 2022