Postdoctoral Fellowship in Single Cell and Synthetic Biology

Bemærk at denne jobannonce er udløbet!
Annoncen er udløbet, og stillingen kan ikke længere søges. Opslaget vises udelukkende som reference

The Schmidt group at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, invites applications from outstanding candidates who are interested in joining our group as a postdoctoral fellow. The position is available from 1 August 2022, or as soon as possible thereafter.

Research project
Research in the Schmidt group focuses on  transcriptional coordination of macrophage diversity and plasticity in metabolic health and disease. For this, we combine single cell analyses of clinical samples and viral targeting strategies in animal models. In a project recently funded by the Lundbeck Foundation, we will develop a new method for generation of cell type specific viral drivers.

The recent explosion in single cell sequencing technologies has unravelled a remarkable heterogeneity and plasticity of cell types within and across organs throughout the body, however, tools to specifically target specific cell types and states to explore their importance for development, physiology, and homeostasis are lacking. In this project, you will help bridge this gap by developing and testing different computational and experimental strategies for learning the cis regulatory code of specific cell types in vivo. This knowledge will be transformed into a method for rapid development of synthetic viral drivers and single cell assessment of their cell type specificity.

We expect the project to outline a general strategy for rapid development of tools to study rare cell types in their in vivo context. This may involve loss of function studies by delivery of RNAi or CRISPR systems for single gene studies or for pooled single cell screens or lineage tracing by delivery of fluorescence markers. The project thereby also has the potential to improve specificity of gene therapies in the future.

Postdoc qualifications/requirements
We are looking for a highly motivated, dedicated, and ambitious candidate with:

  • A PhD degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Biology.
  • Experience with cell biology or NGS data analysis. Experience with cloning, virus production, animal work, and/or transcriptional regulation is considered an advantage.
  • Documented experience leading a research project.
  • Strong communication and collaborative skills and a desire to work in an interdisciplinary environment.
  • Proficiency in spoken and written English.

 

Deadline: 1 June 2022.

Please see the full call, including how to apply, on www.sdu.dk.

Skriv i din ansøgning, at du fandt jobbet på ofir.dk


Postdoctoral Fellowship in Single Cell and Synthetic Biology

The Schmidt group at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, invites applications from outstanding candidates who are interested in joining our group as a postdoctoral fellow. The position is available from 1 August 2022, or as soon as possible thereafter.

Research project
Research in the Schmidt group focuses on  transcriptional coordination of macrophage diversity and plasticity in metabolic health and disease. For this, we combine single cell analyses of clinical samples and viral targeting strategies in animal models. In a project recently funded by the Lundbeck Foundation, we will develop a new method for generation of cell type specific viral drivers.

The recent explosion in single cell sequencing technologies has unravelled a remarkable heterogeneity and plasticity of cell types within and across organs throughout the body, however, tools to specifically target specific cell types and states to explore their importance for development, physiology, and homeostasis are lacking. In this project, you will help bridge this gap by developing and testing different computational and experimental strategies for learning the cis regulatory code of specific cell types in vivo. This knowledge will be transformed into a method for rapid development of synthetic viral drivers and single cell assessment of their cell type specificity.

We expect the project to outline a general strategy for rapid development of tools to study rare cell types in their in vivo context. This may involve loss of function studies by delivery of RNAi or CRISPR systems for single gene studies or for pooled single cell screens or lineage tracing by delivery of fluorescence markers. The project thereby also has the potential to improve specificity of gene therapies in the future.

Postdoc qualifications/requirements
We are looking for a highly motivated, dedicated, and ambitious candidate with:

  • A PhD degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Biology.
  • Experience with cell biology or NGS data analysis. Experience with cloning, virus production, animal work, and/or transcriptional regulation is considered an advantage.
  • Documented experience leading a research project.
  • Strong communication and collaborative skills and a desire to work in an interdisciplinary environment.
  • Proficiency in spoken and written English.

 

Deadline: 1 June 2022.

Please see the full call, including how to apply, on www.sdu.dk.

Skriv i din ansøgning, at du fandt jobbet på ofir.dk


+

Mere af samme slags?

Modtag jobannoncer der minder om dette job i din indbakke.




Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.