Scientist for stem cell process development and analysis

  • Research
  • Måløv

 

   

Do you want to play a significant role in the process development for stem cell GMP manufacturing and do you have experience with pluripotent stem cells, genome editing and molecular assays? Then this job will be just right for you.

 

About the department 

The department Stem Cell Process Development is part of Novo Nordisk’s newly established Stem Cell R&D unit, where we develop novel cell replacement therapies for the treatment of serious chronic diseases. Our department focuses on the development of stem cell manufacturing processes and related analyses. We control processes across the entire pluripotent stem cell workflow, starting with cell line derivation and ending with an efficacious and well-characterised product. Diabetes mellitus type 1, Parkinson’s disease and chronic heart failure are only some of the indications we are currently working on. You will join an international and dedicated group of around 35 employees, including scientists, project leaders, laboratory technicians and student workers. We have expertise in bioprocess development, stem cell biology and GMP compliance and truly believe that stem cell therapies will make a difference in the lives of patients suffering from chronic diseases. If this awakens your interest, please apply and support us in progressing our stem cell projects into the clinic

 

The position

As a scientist in Stem Cell Process Development your key responsibilities will be in developing manufacturing processes and analytical methods for human pluripotent stem cell-based products and gene edited derivatives. The successful candidate independently plans and executes process and -molecular assay development, characterisation studies as well as performs data collection, -analysis and -interpretation. The position will also cover designing experiments and coordination with laboratory technicians and associates, as well as the responsibility for ensuring a successful technical transfer of the processes to relevant manufacturing sites. The latter includes preparation of study reports, technical transfer documentation and hands-on/classroom training of the receiving facility.

 

As a major part of the job responsibility includes hands on processes and assay development, the preferred candidate is a highly motivated researcher with desire to work in a laboratory-focused role.

 

You will work in close collaboration across the organisation with skilled colleagues from research, manufacturing, analytics, virology, raw materials, QA and RA to ensure progress and alignment in our projects according to timelines.

 

Qualifications

You must hold a scientific academic degree in life sciences (human biology, biochemistry, pharmaceutical sciences or other relevant discipline) at master level or above, preferably combined with minimum a few years relevant experience. You have a strong background in cell and molecular biology with extensive experience in expansion and differentiation of stem cells, particularly human pluripotent stem cells (hPSCs) in adherent and/or suspension-based culture systems.

 

The ideal candidate in addition has:

  • Experience in developing and optimising stem cell processes ensuring that desired quality and target cell characteristics are maintained.
  • Experience with Molecular biology techniques, particularly qPCR, ddPCR, NGS, and other gene expression methods
  • Familiarity with generation and interpretation of large datasets
  • Hands on knowledge of cutting-edge techniques in the field of reprogramming.
  • Gene editing experience (CRISPR/Cas9, TALEN, etc) including cell transfection and transduction
  • Experience with DOE models and background in using statistical software (JMP, Minitab, Prism or others)
  • Experience in maintaining organized and detailed up-to-date electronic lab notebook records to support internal documentation needs
  • Attention for details, and drive for problem solving
  • Excellent time management skills and the ability to multitask and contribute to multiple projects under demanding timelines

 

Additional experience of value:

  • Proven successful development of process and analytical methods, preferably for cell therapy products
  • Familiarity with risk assessments such as FMEA and designing, streamlining, and characterizing processes in the Quality by Design space
  • Working in a CMC setting, including writing procedures and development reports.
  • Support technology transfer of optimized cell manufacturing processes to cGMP-compliant manufacturing facilities within the company or to CMOs
  • Knowledge within regulatory requirements of Good Manufacturing Practices (cGMP)

 

Since we are working in an international environment; proficiency in English, both written and spoken, is a prerequisite.

 

As a person, you are open-minded and a good communicator by nature. You have a high level of energy that drives you and inspires your colleagues. You thrive in a changing and dynamic work environment, and in a job that requires you to be flexible, take initiatives and think out of the box when challenges occur. You are a true team-player who enjoys working in close collaboration with colleagues in and out of the laboratory.

 

Working at Novo Nordisk 

At Novo Nordisk, your skills, dedication and ambition help us change lives for the better for patients around the world. In exchange, we offer you an opportunity to work with extraordinary talent and to benefit from a range of possibilities for professional and personal development.

 

Contact

For further information, please contact Arvind Pradip; phone +45 30 79 67 24 or Pernille Linnert Jensen; phone: +45 30 75 00 78.

 

Deadline

August 1st 2020

 

Millions rely on us
To work for Novo Nordisk you will need the skills, dedication and ambition to change lives for the better for millions of patients living with diabetes and other chronical diseases. In exchange, we offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.


Du har ikke vedlagt dokumenter til din ansøgning. Klik på 'OK' knappen nedenfor for at sende din ansøgning alligevel, eller klik på knappen "Annuller" og vedhæft dokumenter, før du sender din ansøgning igen.

Modtag jobannoncer der minder om dette job i din indbakke.Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.

Mere af samme slags?

Modtag jobannoncer der minder om dette job i din indbakke.




Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.

Andre job der matcher din søgning

Research Scientist within Kidney Disease for Diabetes, Cardio-Renal and Translational Research

Novo Nordisk A/S

Måløv
BackSHARE 16 06 2020 in collaboration with Research Scientist within Kidney Disease for Diabetes, Cardio-Renal and Translational Research Where to applyContactSave to favorites Show on map Where to apply Research Scientist within Kidney Disease for ...
Indrykket:2. juli 2020

Tenure Track Researcher/Senior Researcher in land-use greenhouse gas emission research (LULUCF)

Aarhus Universitet

Roskilde
The Department of Environmental Science at Aarhus University, Roskilde, invites applications for a position as Tenure Track Researcher Senior Researcher within greenhouse gas emissions from land-use change (LULUCF Land Use, Land Use Change and Fores...
Indrykket:3. juli 2020

Postdoc in Deep Learning based MRI Image Analysis and Outcome Prediction

Hvidovre Hospital

Hvidovre
Your profile: You should be a creative and enthusiastic researcher with: A PhD degree in computer science, data science, engineering, physics, biomedical sciences or a related field. A clear interest in image analysis using machine learning and deep...
Indrykket:26. juni 2020

Head of Department for Globe Institute, The Faculty of Health and Medical Sciences, University of Copenhagen

KU - SUND - PANUM KBH N

København N
The Faculty of Health and Medical Sciences at University of Copenhagen is one of the largest health and medical science faculties in Europe, and a powerful player in the increasing competition for research talents and external research grants. Resea...
Indrykket:26. juni 2020

Postdoc in Human Aging Interventions in the Scheibye-Knudsen Group Department of Cellular and Molecular Medicine

KU - SUND - PANUM KBH N

København N
We are looking for a highly motivated and dynamic researcher for a two-year position commencing on 1 September 2020. The candidate will investigate interventions in humans that may slow the pace of aging. Information on the department can be found o...
Indrykket:23. juni 2020

Mere af samme slags?

Modtag jobannoncer der minder om dette job i din indbakke.




Når du tilmelder dig accepterer du samtidig vores privatlivspolitik. Du kan altid trække dit samtykke tilbage.

Andre job der matcher din søgning

Research Scientist within Kidney Disease for Diabetes, Cardio-Renal and Translational Research

Novo Nordisk A/S

Måløv
BackSHARE 16 06 2020 in collaboration with Research Scientist within Kidney Disease for Diabetes, Cardio-Renal and Translational Research Where to applyContactSave to favorites Show on map Where to apply Research Scientist within Kidney Disease for ...
Indrykket:2. juli 2020

Tenure Track Researcher/Senior Researcher in land-use greenhouse gas emission research (LULUCF)

Aarhus Universitet

Roskilde
The Department of Environmental Science at Aarhus University, Roskilde, invites applications for a position as Tenure Track Researcher Senior Researcher within greenhouse gas emissions from land-use change (LULUCF Land Use, Land Use Change and Fores...
Indrykket:3. juli 2020

Postdoc in Deep Learning based MRI Image Analysis and Outcome Prediction

Hvidovre Hospital

Hvidovre
Your profile: You should be a creative and enthusiastic researcher with: A PhD degree in computer science, data science, engineering, physics, biomedical sciences or a related field. A clear interest in image analysis using machine learning and deep...
Indrykket:26. juni 2020

Head of Department for Globe Institute, The Faculty of Health and Medical Sciences, University of Copenhagen

KU - SUND - PANUM KBH N

København N
The Faculty of Health and Medical Sciences at University of Copenhagen is one of the largest health and medical science faculties in Europe, and a powerful player in the increasing competition for research talents and external research grants. Resea...
Indrykket:26. juni 2020

Postdoc in Human Aging Interventions in the Scheibye-Knudsen Group Department of Cellular and Molecular Medicine

KU - SUND - PANUM KBH N

København N
We are looking for a highly motivated and dynamic researcher for a two-year position commencing on 1 September 2020. The candidate will investigate interventions in humans that may slow the pace of aging. Information on the department can be found o...
Indrykket:23. juni 2020