Special Consultant, Mass Spectrometry

About the Proteomics Program

The Proteomics Program aims to ensure that Novo Nordisk Foundation Center for Protein Research (CPR) retains world-leading mass spectrometry technology in-house, to provide technical support and maintenance for the Proteomics Program, and to provide analytical proteomics support for CPR research groups.

Responsibilities

As a mass spectrometry specialist in Matthias Mann’s clinical proteomics group, your main responsibilities will be:

• Conducting sample preparation and protein extraction using different protocols from different sample types (i.e. tissue, cell lines, plasma, serum)
• Performing mass-spectrometry based proteomics analysis on body fluids and/or tissue samples, also in collaboration with hospitals for clinical applications
• Maintaining and troubleshooting of different nano-flow HPLC systems: Easy nLC 1200, Evosep, Vanquish Neo
• Maintaining , troubleshooting of different mass spectrometers: Exploris 480, Orbitrap Astral (Thermo) and TimsTOF instruments (Bruker)
• Ensuring the best performance of instruments and coordinating projects with researchers
• Providing on-site repair, maintenance, qualification, testing and validation of above mentioned MS and LC systems.

This may include: Cleaning of instruments, advanced troubleshooting, refurbishing, ordering spare-parts and instrumental components replacement

• Coordinating MS and LC services and repair; and for provision of advanced maintenance work
• Communicating with MS and LC developers, customer service teams, and other personnel to expedite problem resolution
• Maintaining and troubleshooting the automated sample preparation robots
• Performing diagnostics and evaluation of various instruments/methods in collaboration with CPR research groups
• Supporting other researchers within the group with their mass spectrometry-based experiments, providing technical expertise and guidance as needed
• Actively participating in networks with the international research community in general and the Danish research community in particular

Profile

We are looking for a highly motivated and enthusiastic person with the following competencies and experience:

Required qualifications:

• Extensive and proven experience with liquid chromatography and mass-spectrometry based proteomics
• Extensive experience with troubleshooting, cleaning and maintenance of MS instruments
• Experience in with bioinformatics systems and programming (e.g Python)
• Evaluation and assessment of the performance of high resolution Orbitrap and Bruker TIMS-TOF instruments
• Good technology/methodology development record, plus proven and successful experience from laboratories/institutions of high scientific standard
• Experience with guiding and supervising technical staff
• Service-minded and team-player

Place of employment

The place of employment is at Novo Nordisk Foundation Center for Protein Research (CPR), University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and core facilities.

Terms of salary and employment

The employment is a full time, and will be as special consultant (specialkonsulent), in accordance with the provisions of the collective agreement between the Danish Government and AC (the Danish Confederation of Professional Associations), with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.

Employment period: 1 June 2024 – 31 December 2026

For further information about the position, please contact Camilla Johansson, [email protected]

Application

The application must be submitted in English and must include the following documents:

• Application, including motivations for applying for this position (Maximum 2 pages)
• Curriculum vitae
• Diplomas (Master’s, PhD, and other relevant certificates)

Application deadline: 26 April 2024



UCPH is in the process of designing a new shared administrative organisation at UCPH, which is expected to lead to changes within the next 12 - 18 months. The purpose of the administrative reform is, among other things, to strengthen cross-organisational cooperation, increase efficiency, and ensure good career paths for administrative staff members at UCPH. The reform will lead to cutbacks on administration. You are encouraged to contact [manager's name and telephone number + possibly staff representative's name] to learn more about the connection between this position and the administrative reform.